This long term programme requires ambitious construction in difficult, varied and often underdeveloped markets, and GSK wants to bring best practice to all new facilities to minimise cost and delivery in an unprecedented time frame. A challenge of ‘zero incident, zero defect, zero waste’ has been set for the delivery of the new facilities. Furthermore, the status quo of delivering using tried and tested procurement routes was to be abandoned in favour of a higher risk but transparent alternative of building the required expertise in-house and retaining GSK control of facility design, construction, operation / maintenance and critical cost transparency and learning.